Peptide ChooserAcetyl hexapeptide-8 vs Palmitoyl pentapeptide-4
Both are sold as a cosmetic. At the shops we show, Palmitoyl pentapeptide-4 is cheaper per mg: $0.14/mg against $0.49/mg.
Checked 30 Oct 2026Peptide Chooser editorial team. Statuses come from the FDA lists; prices are the lowest we show, per mg at the shops or per month at the online clinics.
| Acetyl hexapeptide-8Cosmetic | Palmitoyl pentapeptide-4Cosmetic | |
|---|---|---|
| FDA status | Cosmeticcosmetics are regulated but do not need FDA approval to be sold. FDA source, 30 Oct 2026 | Cosmeticcosmetics are regulated but do not need FDA approval to be sold. FDA source, 30 Oct 2026 |
| Goal pages | Skin | Skin |
| Lowest price at shops | $0.49/mglowest of 5 shops | $0.14/mglowest of 5 shops |
| Clinic plans from | Not applicable | Not applicable |
| Forms sold | vial | vial, pen |
| What the goal page says | Sold as "Botox in a bottle"; barely gets through the skin. | The most common "anti-wrinkle peptide" in creams. Modest effect in small studies. |
| FDA letters | FDA warning letterslisted by company, not by substance | FDA warning letterslisted by company, not by substance |
| Guides | No guide names it | No guide names it |
Our pages on each: Acetyl hexapeptide-8 and Palmitoyl pentapeptide-4. We do not link to the shops or the clinics.