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Semaglutide vs tirzepatide: what online clinics charge for each.

Peptide Chooser editorial team. Checked 2 Nov 2026.

Short answer

At the online clinics we track, the monthly plans start at: Wegovy from $1491, Zepbound from $2992, compounded semaglutide from $603 and compounded tirzepatide from $904. Wegovy and Zepbound are FDA approved for weight management; Ozempic and Mounjaro are approved for type 2 diabetes.5678 Compounded copies are not FDA approved.9

What are semaglutide and tirzepatide?

Both act on the body's receptors for gut hormones. Semaglutide acts on one, the GLP-1 receptor;7 tirzepatide acts on two, the GIP and GLP-1 receptors.8

Each is sold under more than one brand name: semaglutide as Ozempic, Rybelsus and Wegovy, tirzepatide as Mounjaro and Zepbound.1011

Which brands are approved for weight loss?

  • Wegovy (semaglutide): to reduce excess body weight and keep it off in adults with obesity, or with overweight and a weight-related condition, and to lower the risk of heart attack and stroke in some adults.5
  • Zepbound (tirzepatide): to reduce excess body weight and keep it off in the same groups, and to treat moderate to severe sleep apnea in adults with obesity.6
  • Ozempic (semaglutide): for blood sugar in adults with type 2 diabetes, and to lower heart risk in some of them.7
  • Mounjaro (tirzepatide): for blood sugar in adults and children aged 10 and over with type 2 diabetes.8

Some clinics sell Ozempic plans too, as the table below shows. The label tells you what the FDA approved each brand for.

What do clinics charge for semaglutide?

Every semaglutide plan at the online clinics we track, brand and compounded, cheapest first, checked 2 Nov 2026:

ClinicPlanWhat it isPer monthFDA letterChecked
Mochi HealthCompounded SemaglutideCompounded, not FDA approved$603care fee not knownnone2 Nov 2026
AlloyCompounded SemaglutideCompounded, not FDA approved$7012+ $99/mo carenone2 Nov 2026
AlloyWegovy PillWegovy, FDA approved$1491+ $99/mo carenone2 Nov 2026
SesameWegovy PenWegovy, FDA approved$14913+ $99/mo carenone2 Nov 2026
SesameWegovy PillWegovy, FDA approved$14914+ $99/mo carenone2 Nov 2026
Zappy HealthCompounded SemaglutideCompounded, not FDA approved$15915all-inFDA letter 20 Feb 20262 Nov 2026
Fifty 410Compounded SemaglutideCompounded, not FDA approved$19916all-inFDA letter 20 Feb 20262 Nov 2026
Direct MedsCompounded SemaglutideCompounded, not FDA approved$29717all-inFDA letter 9 Sep 20252 Nov 2026
FoundWegovy PenWegovy, FDA approved$65018care fee not knownnone2 Nov 2026
FoundOzempic PenOzempic, FDA approved$1,10019care fee not knownnone2 Nov 2026
WellMedrOzempic PenOzempic, FDA approved$1,39920care fee not knownnone2 Nov 2026
FridaysOzempic PenOzempic, FDA approved$1,49821care fee not knownnone2 Nov 2026

What do clinics charge for tirzepatide?

ClinicPlanWhat it isPer monthFDA letterChecked
Mochi HealthCompounded TirzepatideCompounded, not FDA approved$904care fee not knownnone2 Nov 2026
AlloyCompounded TirzepatideCompounded, not FDA approved$10022+ $99/mo carenone2 Nov 2026
Good Life MedsCompounded TirzepatideCompounded, not FDA approved$12923care fee not knownnone2 Nov 2026
Fifty 410Compounded Tirzepatide 8-Week ProgramCompounded, not FDA approved$149.5024all-inFDA letter 20 Feb 20262 Nov 2026
Fifty 410Compounded TirzepatideCompounded, not FDA approved$19925all-inFDA letter 20 Feb 20262 Nov 2026
Zappy HealthCompounded TirzepatideCompounded, not FDA approved$27926all-inFDA letter 20 Feb 20262 Nov 2026
AlloyZepbound KwikPenZepbound, FDA approved$2992+ $99/mo carenone2 Nov 2026
SesameZepbound KwikPenZepbound, FDA approved$29927+ $99/mo carenone2 Nov 2026
SesameZepbound VialZepbound, FDA approved$29928+ $99/mo carenone2 Nov 2026
Direct MedsCompounded TirzepatideCompounded, not FDA approved$39929all-inFDA letter 9 Sep 20252 Nov 2026

A clinic with an FDA warning letter is still listed; the chip opens our letters page. Prices are the clinics' published monthly prices; "from" prices are the lowest shown.

What does the care fee add?

Under each price is the clinic's care fee: "all-in" when the price includes the prescriber and check-ins, a monthly amount when it is charged on top, or "care fee not known" when the clinic's page did not say. 8 of the plans above add a fee on top. Add it before you compare two plans.

What does the price not tell you?

  • Whether the price goes up as the dose goes up. Ask the clinic.
  • For a compounded plan, which pharmacy makes it. The FDA does not check a compounded medicine before it is sold.9
  • Whether a compounded semaglutide is a salt form, which the FDA says is a different ingredient from the one in the approved drugs.30

Our guides on compounded semaglutide prices and compounded vs brand GLP-1 go further. None of this is medical advice; your prescriber can tell you which medicine fits you.

What to do next

Compare clinic pricesCompounded vs brand guide

Sources

  1. Alloy, Wegovy Pill, 2 Nov 2026: https://www.myalloy.com/weight
  2. Alloy, Zepbound KwikPen, 2 Nov 2026: https://www.myalloy.com/weight
  3. Mochi Health, Compounded Semaglutide, 2 Nov 2026: https://joinmochi.com/lp/per-dosage-pricing
  4. Mochi Health, Compounded Tirzepatide, 2 Nov 2026: https://joinmochi.com/lp/per-dosage-pricing
  5. FDA drug label for Wegovy, Indications and Usage, through openFDA, effective 23 Apr 2024: https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22WEGOVY%22
  6. FDA drug label for Zepbound, Indications and Usage, through openFDA, effective 28 Aug 2026: https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22ZEPBOUND%22
  7. FDA drug label for Ozempic, Indications and Usage, through openFDA, effective 30 Jan 2026: https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22OZEMPIC%22
  8. FDA drug label for Mounjaro, Indications and Usage, through openFDA, effective 29 Jul 2026: https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22MOUNJARO%22
  9. FDA, Compounding and the FDA: Questions and Answers: https://www.fda.gov/drugs/human-drug-compounding/compounding-and-fda-questions-and-answers
  10. FDA status of Semaglutide (Ozempic, Wegovy) in the Peptide Chooser database, first seen 19 Oct 2026: https://api.fda.gov/drug/drugsfda.json?search=products.active_ingredients.name%3A%22Semaglutide%22&limit=100
  11. FDA status of Tirzepatide (Zepbound, Mounjaro) in the Peptide Chooser database, first seen 19 Oct 2026: https://api.fda.gov/drug/drugsfda.json?search=products.active_ingredients.name%3A%22Tirzepatide%22&limit=100
  12. Alloy, Compounded Semaglutide, 2 Nov 2026: https://www.myalloy.com/weight
  13. Sesame, Wegovy Pen, 2 Nov 2026: https://sesamecare.com/service/online-weight-loss-program
  14. Sesame, Wegovy Pill, 2 Nov 2026: https://sesamecare.com/service/online-weight-loss-program
  15. Zappy Health, Compounded Semaglutide, 2 Nov 2026: https://zappyhealth.com/glp1-pricing/
  16. Fifty 410, Compounded Semaglutide, 2 Nov 2026: https://fifty410.com/pricing
  17. Direct Meds, Compounded Semaglutide, 2 Nov 2026: https://directmeds.com/pricing
  18. Found, Wegovy Pen, 2 Nov 2026: https://joinfound.com/plans-and-pricing
  19. Found, Ozempic Pen, 2 Nov 2026: https://joinfound.com/plans-and-pricing
  20. WellMedr, Ozempic Pen, 2 Nov 2026: https://www.wellmedr.com/pages/get-started-weight-loss
  21. Fridays, Ozempic Pen, 2 Nov 2026: https://joinfridays.com/pricing
  22. Alloy, Compounded Tirzepatide, 2 Nov 2026: https://www.myalloy.com/weight
  23. Good Life Meds, Compounded Tirzepatide, 2 Nov 2026: https://www.goodlifemeds.com/weight-loss
  24. Fifty 410, Compounded Tirzepatide 8-Week Program, 2 Nov 2026: https://fifty410.com/pricing
  25. Fifty 410, Compounded Tirzepatide, 2 Nov 2026: https://fifty410.com/pricing
  26. Zappy Health, Compounded Tirzepatide, 2 Nov 2026: https://zappyhealth.com/glp1-pricing/
  27. Sesame, Zepbound KwikPen, 2 Nov 2026: https://sesamecare.com/service/online-weight-loss-program
  28. Sesame, Zepbound Vial, 2 Nov 2026: https://sesamecare.com/service/online-weight-loss-program
  29. Direct Meds, Compounded Tirzepatide, 2 Nov 2026: https://directmeds.com/pricing
  30. FDA, FDA's Concerns with Unapproved GLP-1 Drugs Used for Weight Loss, current as of 1 Oct 2026: https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/fdas-concerns-unapproved-glp-1-drugs-used-weight-loss